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The Ultimate Guide to FDA-Approved CXL Treatment

The Ultimate Guide to FDA-Approved CXL Treatment

Keratoconus is a progressive eye disease that’s characterized by a change of shape of the cornea due to thinning and weakness of its inner tissue. Standard treatment uses corrective lenses to adapt to changing vision — without slowing the progress of the condition. 

Corneal cross-linking (CXL) is the first treatment approved by the U.S. Food and Drug Administration (FDA) to slow or stop the progress of keratoconus. 

At Advanced Lasik in Midtown East, New York City, and Duarte and Long Beach, California, ophthalmologist Dr. Randa Garrana is at the leading edge of vision correction technology, making our practice an exclusive destination for the most advanced eye care techniques. 

Corneal cross-linking (CXL)

The thinning of the cornea due to keratoconus leads to distortion of the cornea, one of the key light-focusing components of the eye. Left unchecked, this thinning progresses and vision deteriorates to the point where the only option is a corneal transplant

Corneal cross-linking reinforces corneal tissue by exposing drops of riboflavin, also known as vitamin B2, to a specialized ultraviolet (UV) light source. The process creates new connections, or cross links, to bolster collagen proteins in the eyes, strengthening and stabilizing corneal tissue. 

While CXL won’t correct existing corneal damage, it can slow or stop the progression of keratoconus. Dr. Garrana determines your candidacy for the CXL procedure with a thorough evaluation of your condition. 

What FDA approval means

There are variations in the CXL field. Choosing a provider — like Advanced Lasik — that uses this FDA-approved technique means you’re receiving specialist care that’s been fully evaluated for effectiveness and safety using a standardized process to ensure the best level of care possible. 

Are you a candidate for CXL? 

CXL is suitable for keratoconus patients who have measurable changes in their visual prescription, corneal thickness, and corneal shape. The earlier in the course of the disease you receive a diagnosis, the wider your range of treatment options. 

Keratoconus may start as early as your late teens, underscoring the importance of regular eye exams. The sooner you’re diagnosed, the earlier corneal deterioration can be halted. 

What to expect from the CXL procedure

There are basically three steps to the current FDA-approved CXL process: 

  1. Preparation of the corneal surface
  2. Application of riboflavin drops
  3. UV light activation and collagen bonding

For your comfort, we treat your eyes with numbing drops prior to the procedure. A protective lens is placed to aid corneal healing, and then typically removed in a follow-up appointment in the coming weeks. 

You’ll have some discomfort in the first day or two after your procedure, and may be sensitive to light. Corneal stabilization can take weeks to months, so you may experience vision changes during this time. 

Your need for corrective lenses depends on the advancement of keratoconus at the time of your CXL surgery. Dr. Garrana can explain your vision correction options. 

Learn more about corneal cross-linking 

Is CXL your path to protected vision? Book an appointment at your nearest Advanced Lasik location to find out today. We have one East Coast office in Midtown East, New York City, and two West Coast offices in Duarte and Long Beach, California. 

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